Make RBP4 a routine test as an  early warning signal to Diabetes    

Serum retinol binding protein 4 (  RBP4) is a protein that carries retinol in blood. Its role is to deliver RBP4 from liver to surrounding tissues. RBP4 is  also known to be involved in insulin resistance, is produced by mature fat cells . RBP4 is a classic biomarker that is correlated with CVD ( cardiovascular disease) and diabetes.

You need to decrease  RBP4 levels by consuming healthy diet, workout and creating an awareness about an epidemic condition confronting 79 million Americans today. That is one third of the US population, meaning 1 out of every 3 individual is susceptible to an economic, healthcare drain of our already empty Medicaid dollars. Our diet should include fruits, which are low in calories and vegetables which can be sautéed and steamed to our taste. Of course water must be the drink replacing sodas and over advertised caffeine loaded drinks with sugar.  We can add soy products, tofu, tempeh which are rich in protein and vitamins to meet our daily  nutritional requirements.

            It was reported in earlier studies that RBP4 is a early warning / signal for insulin resistance, which may lead to diabetes and cardiovascular disease.  Type 2 diabetes in women and men is pervasive in western world,  Barbara Kahn MD at Harvard medical school speculates diabetes may shorten lifespan in US this century.  Here is what diabetes does, Insulin build-up in cells leads to insulin resistance when  muscle, fat, liver cells fail to act from insulin signal, and  increases  glucose  levels in blood resulting in diabetes. According to Ulf smith a researcher at Goteberg Sweden, people who appear thin and healthy may be susceptible to diabetes due to their genetic predisposition.  RBP4  testing as part of the routine blood analysis can yield important clues to people of all ages including sedentary and overweight population. RBP4 levels have indicated a positive correlation with visceral fat and LDL- cholesterol levels in individuals and was independent of  body weight.

The mantra to prevent or reverse type 2 diabetes is keep moving, follow a set schedule of exercises or walk it off, A simple and easy way to prevent diabetes is only  one hour a day of walking which can lower your  blood pressure,  energize and  burn calories.

Structure of  RBP4 structure in 3D. 

            Celebrities with diabetes have voiced their support to prevent diabetes, Paula Deen the Southern chef features diabetes friendly recipes and raises awareness on her show. Halle Berry is die hard spokesperson who suggests seeking help and advice for diabetes. Many other celebrities' include, Drew Carey,  Gov. mike Huckabee, Larry King, Chaka Khan who is a vegan and lost 60 lbs weight by diet and exercise. Randy Jackson, American idol judge, Tracy Morgan the funny man from Saturday night live ignored warning signs and finally saw light in fight against diabetes. Let it not be you on this list, eat healthy, exercise and enjoy  healthy life.